• 作者：Y. Schoindre^a ; ^{y.schoindre@hopital-foch.org} ; B. Terrier^b ; J.-E. Kahn^a ; D. Saadoun^b ; J.-C. Souberbielle^c ; O. Benveniste^d ; Z. Amoura^b ; J.-C. Piette^b ; P. Cacoub^b ; N. Costedoat-Chalumeau^b
• 关键词：Vitamine D ; Maladies auto-immunes ; Cellules dendritiques ; Lymphocytes T ré ; gulateurs ; Lymphocytes T ; Lymphocytes B ; Autophagie
• 刊名：La Revue de Medecine Interne
• 出版年：2012
• 出版时间：February 2012
• 年：2012
• 卷：33
• 期：2
• 页码：80-86
• 全文大小：513 K

The effects of vitamin D on calcium homeostasis and bone metabolism are well known. In recent years, suboptimal vitamin D status has been recognized as a pandemic. Meanwhile, extra-skeletal effects of vitamin D are becoming better documented, particularly its effects on immunity. The authors present their actions on myeloid dendritic cells, T cells, B cells, as well as on the synthesis of antimicrobial peptides and autophagy, and the potential beneficial effects in autoimmune and inflammatory diseases.