Effect of strategic administration of an encapsulated blend of formic acid, citric acid, and essential oils on Salmonella carriage, seroprevalence, and growth of finishing pigs

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• 作者：Kavita Walia^a ; ^b ; ^e ; Hector Argü ; ello^a ; Helen Lynch^a ; ^c ; ^e ; Finola C. Leonard^c ; Jim Grant^a ; Dermot Yearsley^d ; Sinead Kelly^d ; Geraldine Duffy^a ; Gillian E. Gardiner^b ; ^{ggardiner@wit.ie} ; Peadar G. Lawlor^e
• 关键词：NPSCP ; national pig Salmonella control program ; ILN ; ileocaecal lymph nodes ; MLN ; mesenteric lymph nodes ; ADFI ; average daily feed intake ; ADG ; average daily gain ; FCE ; feed conversion efficiency ; SCFA ; short chain fatty acid ; MCFA ; medium chain fatty acid ; ATP ; adenosine triphosphate ; AMR ; antimicrobial resistance ; TSB ; tryptone soya broth ; PBS ; phosphate buffered saline ; GIT ; gastrointestinal tract ; BPW ; buffered peptone water ; MSRV ; modified semi-solid rappaport-vassiliadis ; XLD ; xylose lysin
• 刊名：Preventive Veterinary Medicine
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：137
• 期：part_PA
• 页码：28-35
• 全文大小：626 K
• 卷排序：137

文摘

Controlling Salmonella at farm level can act as the first line of defence in reducing salmonellosis from pork. This study investigated the efficacy of an encapsulated blend of formic acid, citric acid, and essential oils (FormaXOL™) administered to finisher pigs for 28 days prior to slaughter in controlling Salmonella shedding on a commercial farm with a history of high Salmonella seroprevalence.Fourteen pens of 8–10 pigs/pen were randomly assigned to a control (finisher diet without additive) or a treatment group (the same diet with 4 kg/t of FormaXOL™) for 28 days. Faeces were collected from each pig on days 0, 14, and 28, while on day 29 blood, caecal digesta and ileocaecal-mesenteric lymph nodes were collected at slaughter. Pigs were weighed at the start and end of the trial, feed intake was recorded, and carcass quality parameters were recorded at slaughter.On day 14, Salmonella shedding was reduced in the treatment compared to the control group (27.9% versus 51.7% probability of detecting Salmonella in faeces, respectively; p = 0.001). However, on day 28, no reduction was observed (20.6% versus 35.9% probability of detecting Salmonella in faeces, respectively; p = 0.07). Interestingly, Salmonella shedding rates in the treated pigs remained stable throughout the trial compared to the control group. This suggests that the feed additive prevented additional pigs from acquiring the Salmonella infection. A lower Salmonella seroprevalence was detected at slaughter in the treatment compared to the control group using the 40% optical density cut-off (64.5% versus 88.5%, respectively; p = 0.01). However, no significant differences in Salmonella recovery rates were observed in the caecal digesta or lymph nodes between treated and control groups. Treated pigs had a lower feed intake than pigs fed the control diet (p = 0.001); however, average daily gain and feed conversion efficiency were not affected by treatment (p = 0.45 and 0.55, respectively). Consequently, supplementing the diet with FormaXOL™ for 28 days increased the feed cost per kg of live-weight gain by €0.08.Overall, results suggest that strategic administration of an encapsulated blend of formic acid, citric acid, and essential oils, to finishing pigs for 28 days prior to slaughter has potential to prevent increased Salmonella shedding at certain time points as well as seroprevalence. However, this additive did not lower intestinal carriage, nor did it reduce seroprevalence to below the cut-off used for the high Salmonella risk category in Ireland (50%) or improve growth performance.