NMDAR-dependent proteasome activity in the gustatory cortex is necessary for conditioned taste aversion
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- 作者：Tali Rosenberga ; Alina Elkobia ; Daniela C. Dieterichb ; Kobi Rosenbluma ; c ; kobir@psy.haifa.ac.il" class="auth_mail" title="E-mail the corresponding author
- 关键词：CTA ; Taste learning ; Consolidation ; NMDAR ; Proteasome
- 刊名：Neurobiology of Learning and Memory
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：130
- 期：Complete
- 页码：7-16
- 全文大小：1452 K
文摘
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Proteasome activity is increased 4 h post-acquisition in the GC.
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This modification in proteasome activity is NMDA and CaMKII dependent.
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Mild GC proteasome inhibition attenuates negative but not positive taste learning.
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Proteasome activity is inherent to cortical dependent memory consolidation.