The simulation of multiphase flow field in implantable blood pump and analysis of hemolytic capability
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- 作者：Tie-yan LI ; Liang YE ; Fang-wen HONG ; Deng-cheng LIU ; Hui-min FAN ; Zhong-min LIU
- 关键词：blood pump ; multiphase flow ; numerical simulation ; hemolytic
- 刊名：Journal of Hydrodynamics, Ser. B
- 出版年：2013
- 出版时间：September, 2013
- 年：2013
- 卷：25
- 期：4
- 页码：606-615
- 全文大小：1083 K
文摘
The numerical simulation of the axial flow impeller blood pump NIVADIII is carried out by using a CFD multiphase flow model. The hydrodynamic performance of the pump and the flow field in the pump are analyzed, and the shear stress distribution is obtained. A hemolytic prediction model based on the shear stress is built based on the calculation results, and it can be used for qua- ntitative predictions of the hemolytic behavior of a blood pump. Hemolysis tests in vitro were performed 6 times with fresh bovine blood. At each time, the flow of the pump NIVADIII is 5 L/min and the outflow tract pressure is 100 mmHg. According to the tests, the plasma free hemoglobin (FHB) content and the hematocrit (HCT) are measured after 0 s, 0.5 s, 1 s, 1.5 s, ¡4 s. At the end of each experiment Normal Index of Hemolysis (NIH) of NIVADIII is calculated. The average of NIH is 0.0055 g/100L, almost identical with that obtained from the hemolytic prediction model. This method can be applied in the selection stage of a blood pump.