Effects of 7-valent pneumococcal conjugate 1 vaccine on the severity of adult 2 bacteremic pneumococcal pneumonia
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- 作者：Amelieke J.H. Cremersa ; Jacques F. Meisb ; c ; Grietje Walravena ; Christa E. van der Gaast-de Jongha ; Gerben Ferwerdaa ; 1 ; Gerben.Ferwerda@radboudumc.nl" class="auth_mail ; Peter W.M. Hermansa ; 1 ; 2
- 关键词：Pneumococcal vaccination ; Severity of disease ; Pneumococcal serotypes ; Bacteremic pneumococcal pneumonia
- 刊名：Vaccine
- 出版年：30 June 2014
- 年：2014
- 卷：32
- 期：31
- 页码：3989-3994
- 全文大小：868 K
文摘
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Introduction of pediatric PCV7 reduced adult pneumococcal pneumonia prevalence.
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After PCV7 introduction serotypes 1 and 7F occurred more frequent in adult pneumonia.
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After PCV7 introduction pneumonia was more often accompanied with pleural effusion.
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Pediatric PCV7 did also affect disease severity of adult pneumococcal pneumonia.
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PCV10 introduction will further change the clinical manifestation of adult pneumonia.