The bactericidal effect of carbon nanotube/agar composites irradiated with near-infrared light on Streptococcus mutans

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• 作者：Tsukasa Akasaka ; Makoto Matsuoka ; Takeshi Hashimoto ; Shigeaki Abe ; Motohiro Uo ; Fumio Watari
• 关键词：Carbon nanotubes ; Streptococcus mutans ; Bactericidal activity ; Near-infrared light
• 刊名：Materials Science and Engineering: B
• 出版年：2010
• 出版时间：15 October 2010
• 年：2010
• 卷：173
• 期：1-3
• 页码：187-190
• 全文大小：368 K

文摘

Dental caries are mainly associated with oral pathogens, and Streptococcus mutans is a primary cariogenic organism. Many methods have been established to eliminate S. mutans from the oral cavity. This study aimed to evaluate the effect of carbon nanotube (CNT)/agar composites irradiated with near-infrared (NIR) light on S. mutans, as a potential photothermal antimicrobial nanotherapy. A colony-forming unit assay clearly showed that CNT/agar composites attain bactericidal activity after NIR light irradiation; this bactericidal activity is higher than that of graphite (GP)/agar and activated carbon (AC)/agar composites. Furthermore, it was observed that longer irradiation times immobilized S. mutans in the CNT/agar composite.