RHDV virus-like particles (VLPs) are a class of recombinant subunit vaccines.
RHDV VLPs were produced in silkworm pupae.
The amount of RHDV VLPs reached 107 HA units per pupa.
RHDV VLPs are promising vaccines due to strong immunogenicity and safety.
RHDV VLPs resemble native viruses but lack infectious genetic material.