Relationship between DNA damage in liver, heart, spleen and total blood cells and disease pathogenesis of infected rats by Trypanosoma evansi
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- 作者：Matheus D. Baldisseraa ; matheusd.biomed@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author ; Michele R. Sagrillob ; Mariâ ; ngela F. de Sá ; a ; Thirssa H. Grandoa ; Carine F. Souzac ; Gerson F. de Brumb ; Sô ; nia C.A. da Luza ; Sé ; rgio S. Oliveirad ; Adriana L.B. De Mellob ; Ká ; tia Nascimentob ; Etiane Tatsche ; Rafael N. Morescoe ; Aleksandro S. da Silvaf ; Silvia G. Monteiroa
- 关键词：Comet assay ; Genotoxicity ; Trypanosomosis ; Nitric oxide ; DNA damage
- 刊名：Experimental Parasitology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：161
- 期：Complete
- 页码：12-19
- 全文大小：2732 K
文摘
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Trypanosoma evansi infection cause increased frequency damage using comet assay.
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T. evansi infection cause increased damage index using comet assay.
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Histopathological alterations in liver, spleen and heart were observed.
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T. evansi infection causes genotoxicity due to the production of NO.