Melaleuca alternifolia anthelmintic activity in gerbils experimentally infected by Haemonchus contortus
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- 作者：Thirssa H. Grandoa ; thirssa_thi@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Matheus D. Baldisseraa ; Lucas T. Gresslera ; Mariâ ; ngela Facco de Sá ; a ; Bruna N. Bortoluzzia ; Andressa S. Schafera ; Rafael C. Eblingb ; Renata P. Raffinc ; Roberto C.V. Santosa ; c ; Lenita M. Stefanid ; Rodrigo Vaucherc ; Marta L.R. Lealb ; Silvia G. Monteiroa ; sgmonteiro@uol.com.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antiparasitic ; Gerbil ; H. contortus ; Melaleuca essential oil ; Phytotherapy
- 刊名：Experimental Parasitology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：170
- 期：Complete
- 页码：177-183
- 全文大小：1036 K
文摘
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The treatments used were effective on reducing infection by H. contortus in gerbils.
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The nanocarriers used with essential oil of M. alternifolia (nanoTTO) showed highest efficiency.
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Nanotechnology can increase efficacy and bioavailability of therapeutic substances.
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Terpinen-4-ol may protect against liver damage caused by infectious agents.