Dopamine and serotonin transporter availability in chronic heroin users: A [¹²³I]β-CIT SPECT imaging study

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• 作者：Kelly P. Cosgrove ; Karen Tellez-Jacques ; Brian Pittman ; Ismene Petrakis ; Ronald M. Baldwin ; Gilles Tamagnan ; John Seibyl ; Thomas Kosten ; Julie K. Staley
• 关键词：Substance abuse ; Single photon emission computed tomography (SPECT) ; Dopamine transporter ; Serotonin transporter
• 刊名：Psychiatry Research: Neuroimaging
• 出版年：2010
• 出版时间：30 December 2010
• 年：2010
• 卷：184
• 期：3
• 页码：192-195
• 全文大小：379 K

文摘

Dopamine (DA) and serotonin (5-HT) transporter availability in heroin users and healthy controls was measured using [¹²³I]β-CIT and SPECT imaging. Heroin users had statistically similar striatal DA and brainstem and diencephalon 5-HT transporter availability compared with controls. No associations between transporter availability and heroin use characteristics were found.