New antimicrobial peptides against foodborne pathogens: From in silico design to experimental evidence
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- 作者：Gianna Palmieria ; 1 ; gianna.palmieri@ibbr.cnr.it" class="auth_mail" title="E-mail the corresponding author ; Marco Balestrieria ; 1 ; Yolande T.R. Prorogab ; Lucia Falcignoc ; Angelo Facchianod ; Alessia Riccioa ; Federico Capuanob ; Raffaele Marronee ; Gianluca Negliae ; Aniello Anastasioe
- 关键词：Antimicrobial peptide ; Mitochondrial-targeted peptide ; Listeria monocytogenes ; Food bio-preservatives ; Structural analysis
- 刊名：Food Chemistry
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：211
- 期：Complete
- 页码：546-554
- 全文大小：1412 K
文摘
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An innovative approach to design new antimicrobial peptides is proposed.
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Mitochondrial-targeting peptides (MTPs) could be effective as antimicrobial agents.
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Designed MTPs show bactericidal activity vs the foodborne pathogen L. monocitogenes.
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MTPs represent a new source of templates to project new food bio-preservatives.