Biomarkers and degree of atherosclerosis are independently associated with incident atherosclerotic cardiovascular disease in a primary prevention cohort: The ARIC study
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- 作者：Anandita Agarwalab ; Salim Virania ; c ; David Couperd ; Lloyd Chamblessd ; Eric Boerwinklee ; Brad C. Astorf ; Ron C. Hoogeveenb ; Joe Coreshg ; A. Richey Sharrettg ; Aaron R. Folsomh ; Tom Mosleyi ; Christie M. Ballantyneb ; c ; Vijay Nambia ; b ; c ; vnambi@bcm.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Carotid intima media thickness ; High sensitivity C- reactive protein ; Lipoprotein associated phospholipase A2 ; High sensitivity troponin T ; NT-pro B-type natriuretic peptide ; lipoprotein(a) ; Cardiovascular disease ; Coronary heart disease ; Stroke
- 刊名：Atherosclerosis
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：253
- 期：Complete
- 页码：156-163
- 全文大小：989 K
文摘
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Ultrasound measurements (cIMT/plaque) have been shown to be associated with incident CVD as have serum biomarkers.
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We tested whether atherosclerosis burden measured by cIMT/plaque affects the association of biomarkers with CVD.
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Associations between biomarkers and CVD were not affected by degree of atherosclerosis in this analysis from the ARIC study.