The 68Ge phantom-based FDG-PET site qualification program for clinical trials adopted by FIL (Italian Foundation on Lymphoma)
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- 作者：Stephane Chauviea ; chauvie.s@ospedale.cuneo.it" class="auth_mail" title="E-mail the corresponding author ; Fabrizio Bergesioa ; Federica Fioronib ; Marco Brambillac ; Alberto Biggia ; Annibale Versarib ; Luca Guerrad ; Giovanni Stortoe ; Pellegrino Mustoe ; Stefano Luminarif ; Maria G. Cabrasg ; Monica Balzarottih ; Luigi Rigaccii ; Maurizio Martellij ; Umberto Vitolok ; Massimo Federicof ; Andrea Gallaminil
- 关键词：Quantitative imaging ; Positron emission tomography ; Clinical trials ; Lymphoma
- 刊名：Physica Medica
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：32
- 期：5
- 页码：651-656
- 全文大小：657 K
文摘
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Quantitative Positron Emission Tomography (QPET) could be used as a biomarker.
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Clinical trial qualification (CTQ) of PET scanners is mandatory for reliable use of QPET.
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Variability in activity measurements at 95% CI was 74.0% (18F) and 20.5% (68Ge).
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100% (with 68Ge) and 28% (with 18F) of PET scanners passed CTQ at first round.
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CTQ with 68Ge vs 18F filled phantom assure lower variability and eases the process.