Importance and challenges of accurately counting rotavirus deaths in China, 2002

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• 作者：Eileen L. Yee ; Zhao-Yin Fang ; Na Liu ; Stephen C. Hadler ; Xiaofeng Liang ; Huaqing Wang ; Xu Zhu ; Baoming Jiang ; Umesh Parashar ; Marc-Alain Widdowson ; Roger I. Glass
• 关键词：Rotavirus ; Mortality ; Vaccine
• 刊名：Vaccine
• 出版年：2009
• 出版时间：20 November 2009
• 年：2009
• 卷：27
• 期：Supplement 5
• 页码：F46-F49
• 全文大小：118 K

文摘

Rotavirus mortality is an important component of the total burden of rotavirus disease for children under 5 years old, but accurate estimation is difficult for many developing countries. Here we applied a more direct method to improve estimates of rotavirus mortality in China using 2002 Chinese-specific data. Results indicate that in 2002, approximately 13,400 children under 5 years old in China died from rotavirus and 70 % of these deaths occur in rural areas. Thus, a national rotavirus immunization program targeting rural areas with high mortality from diarrhoea could dramatically reduce these deaths and urban areas could reduce childhood hospitalizations attributed to rotavirus by 43 % .