Epidemiologic analysis of a sarcoid outbreak involving 12 of 111 donkeys in Northern Italy

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• 作者：Hans Abel-Reichwald^a ; ^{tierarztpraxis@abel-reichwald.at} ; Edmund K. Hainisch^a ; ^b ; ^{edmund.hainisch@vetmeduni.ac.at} ; Sophie Zahalka^a ; ^{zahalkas@student.ethz.ch} ; Annunziata Corteggio^c ; ^{a.corteggio@ibp.cnr.it} ; Giuseppe Borzacchiello^d ; ^{borzacch@unina.it} ; Barbara Massa^e ; ^{barbara.massa@ilrifugiodegliasinelli.org} ; Luca Merlone^e ; ^{lucamerlone@hotmail.com} ; Lubna Nasir^f ; ^{Lubna.Nasir@glasgow.ac.uk} ; Faith Burden^g ; ^{faith.burden@thedonkeysanctuary.org.uk} ; Sabine Brandt^a ; ^{sabine.brandt@vetmeduni.ac.at}
• 关键词：Donkey ; Sarcoid ; Bovine papillomavirus ; Transmission ; Genetic variants
• 刊名：Veterinary Microbiology
• 出版年：2016
• 出版时间：30 November 2016
• 年：2016
• 卷：196
• 期：Complete
• 页码：85-92
• 全文大小：736 K
• 卷排序：196

文摘

A sarcoid outbreak in a herd of 111 donkeys was characterized. All sarcoid-affected donkeys, two of 55 tabanids and dandruff from a curry comb tested positive for BPV1/2 E5, yet negative by IC/PCR. IHC revealed different levels of intralesional E5 and L1 expression. A series of BPV1 E5, E2, and LCR variants and BPV2 E5 were detected from donkeys. Intralesional presence of these different variants in the different donkeys indicates that the animals had accidently developed sarcoids at about the same time rather than having acquired disease from each other.