Racial disparities in melanoma survival

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• 作者：Sean M. Dawes ; MPH^a ; Sheena Tsai ; MPH^c ; Haley Gittleman ; MS^d ; Jill S. Barnholtz-Sloan ; PhD^b ; ^c ; Jeremy S. Bordeaux ; MD ; MPH^e ; ^{jeremy.bordeaux@uhhospitals.org" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Asian American/Native American/Pacific Islander ; black ; epidemiology ; health outcomes ; melanoma ; public health ; race ; stage ; survival ; white
• 刊名：Journal of the American Academy of Dermatology
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：75
• 期：5
• 页码：983-991
• 全文大小：1559 K

文摘

Melanoma is a cutaneous malignancy common in the white population but can also occur in other racial groups.

Objective

We sought to evaluate survival across racial groups in patients given a diagnosis of malignant melanoma.

Methods

The Surveillance, Epidemiology, and End Results database was used to populate a cohort of 96,953 patients given a diagnosis of cutaneous melanoma as their primary cancer, from 1992 to 2009.

Results

White patients had the longest survival time (P < .05), followed by Hispanic (P < .05), Asian American/Native American/Pacific Islander (P < .05), and black (P < .05) patients, respectively. Survival stratified by race and stage showed that for stages I and III, blacks had a significantly lower survival (P < .05), and increased hazard ratios (stage I hazard ratio, 3.037 [95% confidence interval, 2.335-3.951]; stage III hazard ratio, 1.864 [95% confidence interval, 1.211-2.87]). The proportion of later stage cutaneous melanoma (stages II-IV) was greater in blacks compared with whites.

Conclusion

Despite higher incidence of cutaneous melanoma in whites, overall survival for cutaneous melanoma in non-whites was significantly lower. Our results suggest that more emphasis is needed for melanoma screening and awareness in non-white populations to improve survival outcomes.