Glycoside nucleoside lipids (GNLs): An intrusion into the glycolipids?world?

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• 作者：Laurent Latxague^a ; ^c ; Marie-José ; Dalila^a ; ^c ; Amit Patwa^a ; ^c ; Sophia Ziane^b ; ^c ; Olivier Chassande^b ; ^c ; Guilhem Godeau^a ; ^c ; Philippe Barthé ; lé ; my^a ; ^c ; ^{philippe.barthelemy@inserm.fr}
• 关键词：Amphiphile ; Nucleoside ; Lipid ; Glycolipids ; Glycoconjugates ; Self-assembly ; Liposomes
• 刊名：Comptes Rendus Chimie
• 出版年：2012
• 出版时间：January 2012
• 年：2012
• 卷：15
• 期：1
• 页码：29-36
• 全文大小：1269 K

文摘

Glycoside nucleoside lipids (GNLs) are a new class of low-molecular-weight amphiphilic molecules capable of gelling either aqueous or organic solvents. This article provides an overview of some related lipid conjugate properties and the origin of the GNLs?discovery. Finally, recent biological results obtained with two different GNLs demonstrate the great variety of applications they may offer, and how they can find their place in the large glycolipids?community.