Stem cell-dependent formation of a functional anterior regeneration pole in planarians requires Zic and Forkhead transcription factors
详细信息 查看全文
- 作者：Matthias C. Vogga ; b ; Suthira Owlarna ; b ; c ; Yuvia A. Pé ; rez Ricoa ; b ; Jianlei Xied ; Yoko Suzukic ; e ; Luca Gentilee ; Wei Wud ; Kerstin Bartscherera ; b ; kerstin.bartscherer@mpi-muenster.mpg.de" class="auth_mail
- 关键词：Regeneration ; FoxD ; Zic ; Notum ; Follistatin ; Stem cell differentiation ; Planaria
- 刊名：Developmental Biology
- 出版年：15 June 2014
- 年：2014
- 卷：390
- 期：2
- 页码：136-148
- 全文大小：3565 K
文摘
- •
zicA is a FoxD-dependent regulator of planarian head regeneration.
- •
Expression of Wnt and TGF-尾 antagonists notum and follistatin at the anterior pole depends on zicA and FoxD.
- •
A zicA/FoxD-expressing stem cell lineage forms the anterior regeneration pole.