Neuroendocrine tumors of the small bowel: evaluation with MR-enterography

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• 作者：Anthony Dohan^a ; ^b ; ^c ; ^{anthony.dohan@lrb.aphp.fr" class="auth_mail" title="E-mail the corresponding author} ; Hassan El Fattach^a ; ^{hassangreenmed@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Maxime Barat^a ; ^{maxime.barat89@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Youcef Guerrache^a ; ^{youcef.guerrache@aphp.fr" class="auth_mail" title="E-mail the corresponding author} ; Clarisse Eveno^b ; ^c ; ^d ; ^{clarisse.eveno@lrb.aphp.fr" class="auth_mail" title="E-mail the corresponding author} ; Raphael Dautry^a ; ^b ; ^{raphael.dautry@aphp.fr" class="auth_mail" title="E-mail the corresponding author} ; S&eacute ; bastien Mul&eacute ; ^e ; ^{sebastien.mule@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Mourad Boudiaf^a ; ^{mourad.boudiaf@lrb.aphp.fr" class="auth_mail" title="E-mail the corresponding author} ; Christine Hoeffel^e ; ^{choeffel-fornes@chu-reims.fr" class="auth_mail" title="E-mail the corresponding author} ; Philippe Soyer^a ; ^b ; ^c ; ^{philippe.soyer@lrb.aphp.fr" class="auth_mail" title="E-mail the corresponding author}
• 关键词：MR-enterography ; Intestinal neoplasm ; Neuroendocrine tumor ; Small bowel ; Small bowel tumor detection
• 刊名：Clinical Imaging
• 出版年：2016
• 出版时间：May-June 2016
• 年：2016
• 卷：40
• 期：3
• 页码：541-547
• 全文大小：693 K

文摘

To determine the sensitivity of magnetic resonance (MR)-enterography for the detection of neuroendocrine tumors of the small-bowel (NETSB) and analyze the imaging presentation of NETSB on MR-enterography.

Patients & Methods

The MR-enterography studies (including HASTE, TruFISP, and 3D VIBE MR sequences before and after intravenous administration of a gadolinium-chelate) of 19 patients with pathologically confirmed NETSB were blindly reviewed. Images were analyzed with respect to imaging presentation. Sensitivity of MR-enterography as well as that of each individual MR-enterography sequence for the diagnosis of NETSB was estimated with 95% confidence intervals (CIs). Comparisons between individual MR-enterography sequences were performed using the McNemar test.

Results

Twenty-seven NETSBs were confirmed in 19 patients. Overall sensitivity of MR-enterography for NETSB detection was 74% (20/27; 95% CI: 54–89%) on a per-lesion basis. On a per-patient basis, MR-enterography had a sensitivity of 95% (18/19; 95% CI: 74–100%) for the detection of NETSB. Best degrees of sensitivity were achieved with 3D VIBE MR-enterography sequences after intravenous administration of a gadolinium-chelate (Se = 95%; 18/19) by comparison with HASTE (Se = 26%; 5/19) and TruFISP (Se = 26%; 5/19) sequences (P = .00022). Visible focal small-bowel mass, mesenteric stranding, and mesenteric mass were found in 16/19 (84%), 17/19 (89%), and 15/19 (79%) patients, respectively.

Conclusion

MR-enterography shows highly suggestive features for the diagnosis of NETSB and has high degrees of sensitivity for the diagnosis of NETSB on a per-patient basis.