Community-dwelling adults, of diverse socio-economic status, seeking buprenorphine treatment.

A comprehensive neurocognitive battery that evaluated baseline cognitive functioning.

Psychiatric, functional, and psychological factors were examined.

Interpreted overall performance emphasizing the effect of multiple factors on neurocognitive performance.

Adults who present for opioid agonist treatment with buprenorphine, may exhibit diminished neurocognitive functioning. Also, preexisting alcohol and cocaine use disorders are associated with poorer scores.