• 作者：Xavier Juanola Roura^a ; Pedro Zarco Montejo^b ; Jesú ; s Sanz Sanz^c ; Santiago Muñ ; oz Ferná ; ndez^d ; Juan Mulero Mendoza^c ; Luis Francisco Linares Ferrando^e ; Jordi Gratacó ; s Masmitja^f ; Rosario Garcí ; a de Vicuñ ; a^g ; Cristina Fernandez Carballido^h ; Eduardo Collantes Estevezⁱ ; Enrique Batlle Gualda^j ; Rafael Ariza Ariza^k ; Estí ; baliz Loza Santamarí ; a^l ; ^{estibaliz.loza@ser.es}
• 关键词：Consenso ; recomendaciones ; guí ; a ; terapia bioló ; gica ; espondiloartritis
• 刊名：Reumatolog¨ªa Cl¨ªnica
• 出版年：2011
• 出版时间：March-April 2011
• 年：2011
• 卷：7
• 期：2
• 页码：113-123
• 全文大小：218 K

Objective

Due to the amount and variability in quality regarding the use of biologic therapy (BT) in patients with spondyloarthritis (SpA), except for psoriatic arthritis (PsA) patients, the Spanish Society of Rheumatology has promoted the generation of recommendations based on the best evidence available. These recommendations should be a reference for rheumatologists and those involved in the treatment of patients with spondyloarthritis (SpA), except for psoriatic arthritis (PsA), who are using, or about to use BT.

Methods

Recommendations were developed following a nominal group methodology and based on systematic reviews. The level of evidence and grade of recommendation were classified according to the model proposed by the Center for Evidence Based Medicine at Oxford. The level of agreement was established through Delphi technique.

Results

We have produced recommendations on the use of BT currently available for SpA (but not PsA) in our country. These recommendations include disease assessment, treatment objectives, therapeutic scheme and switching.

Conclusions

We present an update on the SER recommendations for the use of BT in patients with SpA, except for PsA.