From multidrug-resistant tuberculosis to DOTS expansion and beyond: making the most of a paradigm shift

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• 作者：Jim Yong Kim ; Joia S. Mukherjee ; Michael L. Rich ; Kedar Mate ; Jaime Bayona ; Mercedes C. Becerra
• 关键词：Resuscitation factor ; Growth promotion ; Dormancy
• 刊名：Tuberculosis
• 出版年：2003
• 出版时间：February 2003
• 年：2003
• 卷：83
• 期：1-3
• 页码：59-65
• 全文大小：98 K

文摘

This review examines the paradigm shift around multidrug-resistant tuberculosis (MDR-TB). This shift has centered largely on the activities of institutions participating in the World Health Organization's Working Group on DOTS-Plus for MDR-TB. We review the important milestones since 1995, namely, the emergence of new evidence, the construction of new mechanisms, and the building of consensus to support new policy guidelines. This paper offers a case study of the construction of a model of good global governance that—if the opportunity is taken—can improve access to effective TB care through improving and helping to expand the WHO-recommended DOTS strategy.