Aspergillus niger does not biosynthesize gliotoxin.
A. niger mediates enzymatic gliotoxin bis-thiomethylation.
This activity is mediated by an inducible thiol methyltransferase.
Gliotoxin bis-thiomethylation in A. niger dysregulates sulphur metabolite levels.
Gliotoxin induces increased abundance of hydrolytic enzymes in A. niger.