Sexual diergism in antibody response to whole virus trivalent inactivated influenza vaccine in outbred mice
详细信息 查看全文
- 作者：Irena Živkovića ; Biljana Bufanb ; Vladimir Petru&scaron ; ića ; Rajna Minića ; Nevena Arsenović-Raninb ; Raisa Petrovića ; Gordana Leposavićc ; Gordana.Leposavic@pharmacy.bg.ac.rs" class="auth_mail" title="E-mail the corresponding author
- 关键词：TIV ; trivalent inactivated vaccine ; HA ; hemagglutinin ; ELISA ; enzyme-linked immunosorbent assay ; BSA ; bovine serum albumin ; PBS ; phosphate-buffered saline ; T-PBS ; PBS containing 0.05% Tween 20 ; OD ; optical density ; RDE ; receptor destroying enzyme ; HAI ; hemagglutination inhibition ; MN ; microneutralization ; TCID50 ; 50% tissue culture infective dose ; MDCK ; Madin&ndash ; Darby canine kidney ; ELISPOT ; enzyme-linked immunospot ; BCIP/NBT ; 5-bromo-4-chloro-3-indolyl-phosphate/nitro blue tetrazolium ; p.i.
- 刊名：Vaccine
- 出版年：2015
- 出版时间：13 October 2015
- 年：2015
- 卷：33
- 期：42
- 页码：5546-5552
- 全文大小：1350 K
文摘
- •
More robust IgM response to TIV in female than in male mice.
- •
More robust H1N1-specific IgG1 response in TIV-immunized female than in male mice.
- •
More robust H1N1 virus-specific neutralizing response in TIV-immunized female mice.
- •
Shift in IgG2a/IgG1 ratio toward the former in TIV-immunized female mice.
- •
Fewer IL-4+, but comparable IFN-γ+ cells TIV-immunized female mice splenocytes.