Astrocytes, microglia/macrophages, and neurons expressing Toll-like receptor 11 contribute to innate immunity against encephalitic Toxoplasma gondii infection
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- 作者：H.T. Atmacaa ; ht_atmaca@yahoo.com" class="auth_mail ; O. Kula ; E. Karaku艧b ; O.S. Terzic ; S. Canpolata ; T. Anteplio臒lua
- 关键词：BCIP/NBT ; 5-bromo-4-chloro-3-indolyl phosphate/nitroblue tetrazolium ; cDNA ; complementary DNA ; DAB ; diaminobenzidine ; DCs ; dendritic cells ; GFAP ; glial fibrillary acidic protein ; HRP ; horseradish peroxidase ; IFN-纬 ; interferon gamma ; IL ; interleukin ; IP ; intraperitoneally ; MHC ; major histocompatibility complex ; MyD88 ; myeloid differentiation factor 88 ; PCR ; polymerase chain reaction ; p.i. ; post-infection ; TBS ; Tris-buffered saline ; TLR ; Toll-like receptor
- 刊名：Neuroscience
- 出版年：6 June 2014
- 年：2014
- 卷：269
- 期：Complete
- 页码：184-191
- 全文大小：2707 K
文摘
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We report Toll-like receptor 11 (TLR11) increasing in Toxoplasma gondii encephalitis.
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We report TLR11 expression is induced in astrocytes, neurons, and microglia.
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Innate immunity of Toxoplasmosis (1/3 of the population is infected) research is increasing.