MiR-34a, a promising novel biomarker for benzene toxicity, is involved in cell apoptosis triggered by 1,4-benzoquinone through targeting Bcl-2

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• 作者：Yujiao Chen^a ; ^b ; ¹ ; Pengling Sun^a ; ^b ; ¹ ; Xiaoli Guo^a ; ^b ; Ai Gao^a ; ^b ; ^{gaoai0980@163.com}
• 关键词：Benzene ; Biomarker ; MiR-34a ; Bcl-2 ; Apoptosis
• 刊名：Environmental Pollution
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：221
• 期：Complete
• 页码：256-265
• 全文大小：1689 K
• 卷排序：221

文摘

MiR-34a regulated benzene-induced hematotoxicity. MiR-34a mediated 1,4-benzoquinone-induced apoptosis via targeting Bcl-2. MiR-34a was considered as major factor to abnormal cell apoptosis, involved in benzene-induced hematotoxicity.