Protective effects of Lactobacillus plantarum on epithelial barrier disruption caused by enterotoxigenic Escherichia coli in intestinal porcine epithelial cells
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- 作者：Yunpeng Wua ; b ; Cui Zhub ; Zhuang Chenb ; Zhongjian Chenb ; Weina Zhangb ; Xianyong Mac ; Li Wangc ; Xuefen Yangc ; Zongyong Jiangb ; c ; jiangz28@qq.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：A20 ; zinc finger protein A20 ; BCA ; bicinchoninic acid ; Bcl3 ; B-cell CLL/lymphoma ; BSA ; bovine serum albumin ; DMEM ; Dulbecco&rsquo ; s Modified Eagle medium ; EGF ; epidermal growth factor ; ETEC ; enterotoxigenic Escherichia coli ; IL-8 ; interleukin-8 ; IPEC-J2 ; intestinal porcine epithelial cell ; IRAK-M ; interleukin-1 receptor-associated kinase-M ; LB ; Luria-Bertani ; L. plantarum ; Lactobacillus plantarum ; MAPK ; mitogen-activated protein kinase ; MKP-1 ; mitogen-activated protein kinase phosphatase-1 ; MOI
- 刊名：Veterinary Immunology and Immunopathology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：172
- 期：Complete
- 页码：55-63
- 全文大小：2883 K
文摘
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L. plantarum partially offset ETEC-K88 induced upregulation of inflammatory cytokines.
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L. plantarum protected against epithelial barrier damage from ETEC-K88.
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The protective effects of L. plantarum likely involve diminished activation of NF-κB and MAPK pathways.