文摘
CX3CR1 ablation improves the life span, body weight, and symptomatic scores of Mecp2KO mice. CX3CR1 ablation improves the respiratory parameters of Mecp2KO mice. CX3CR1 ablation improves the motor performance of Mecp2KO mice. CX3CR1 ablation recovers neuronal or microglial morphology of Mecp2KO mice. CX3CR1 ablation increases the expression of insulin-like growth factor 1 in Mecp2KO mice.