Consequences of constitutive deletion of melanin-concentrating hormone-1 receptors for feeding and foraging behaviors of mice
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- 作者：William J.A. Eiler IIa ; Yanyun Chenb ; Lawrence J. Sliekerb ; Paul A. Ardayfioa ; Michael A. Statnickb ; Jeffrey M. Witkina ; jwitkin@lilly.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：MCH1 ; Feeding ; Motivation ; Mouse
- 刊名：Behavioural Brain Research
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：316
- 期：Complete
- 页码：271-278
- 全文大小：1409 K
文摘
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MCH1 −/− mice exhibited increased motivation to obtain food compared to WT mice.
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Increased food-seeking in MCH1−/− mice was also observed when behavior was punished.
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Feeding in MCH1 −/− mice contrasts in some important dimensions from data reported with MCH1 receptor antagonism.