Behavioural phenotype of histamine H₄ receptor knockout mice: Focus on central neuronal functions

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• 作者：Maria Domenica Sanna^a ; Carla Ghelardini^a ; Robin L. Thurmond^b ; Emanuela Masini^a ; Nicoletta Galeotti^a ; ^{nicoletta.galeotti@unifi.it}
• 关键词：Histamine H4 receptors ; Central nervous system ; Pain ; Anxiety ; Memory ; Feeding
• 刊名：Neuropharmacology
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：114
• 期：Complete
• 页码：48-57
• 全文大小：1118 K
• 卷排序：114

文摘

The behavioural phenotype of H4R-KO has been defined. H4R modulates locomotor activity, anxiety, pain and feeding behaviour. Neuronal H4R has a prominent role in the histaminergic regulation of neuronal functions.