Poly(ethylene glycol)-supported chiral pyridine-2,6-bis(oxazoline): synthesis and application as a recyclable ligand in Cui-catalyzed enantioselective direct addition of terminal alkynes to imines
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- 作者：Elena A. Tarasenko ; Irina P. Beletskaya ; beletska@org.chem.msu.ru
- 刊名：Mendeleev Communications
- 出版年：2016
- 出版时间：November-December 2016
- 年：2016
- 卷：26
- 期：6
- 页码：477-479
- 全文大小：219 K
- 卷排序：26
文摘
Pyridine-2,6-bis(oxazoline) immobilized on a soluble support, viz., poly(ethylene glycol) methyl ether with Mn = 5000 Da, has been synthesized for the first time. The efficiency of its application as a chiral ligand in Cui-catalyzed direct addition of terminal alkynes to imines and the feasibility of its recycling at least in three cycles have been shown.