ID 337 - Response to clonazepam in typical absence status epilepticus

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• 作者：W. Abdellaoui ; S. Bahbouh ; R. Benalia ; M.R. Belabed ; E. Attal ; M. Ait-Kaci-Ahmed
• 刊名：Clinical Neurophysiology
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：127
• 期：3
• 页码：e86-e87
• 全文大小：43 K

文摘

Absence status epilepticus ASE is a type of non convulsive status epilepticus in which continuous or recurrent generalised epileptiform discharges are associated with a varying grade of consciousness.We describe the case of an elderly man who presented with typical ASE resolved after intravenous clonazepam.

Methods

Clinical case report.

Results

A 62-year old man had a history of idiopathic generalised epilepsy with tonic-clonic seizures.Treated since the age of 30 years with phenobarbital PB 100 mg/day.He was disoriented to time and place and a slowness in mental activity over 24 h after food poisoning. Laboratory tests and a CT scan of the brain were normal.brain MRI did not show any structural lesions.EEG showed recurrent generalsed paroxysms of 3 Hz spike-wave.Normal background activity.Normalisation of mental status and EEG pattern after 1mg intravenous clonazepam (Benzodiazepine). Phenobarbital PB was substituted by valproic acid 1500 mg/day.

Conclusion

Typical ASE diagnosis must be based on EEG pattern and clinical history. Efficacy of intravenous clonazepam in treatment of typical ASE.