Lipoblastoma of the Labia: A Case Report

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• 作者：Krista J. Childress ; MD¹ ; ² ; ^{kchildre@bcm.edu" class="auth_mail" title="E-mail the corresponding author} ; John Hicks ; MD¹ ; ³ ; Hao Wu ; MD³ ; Mary L. Brandt ; MD⁴ ; Oluyemisi A. Adeyemi-Fowode ; MD¹ ; ²
• 关键词：Lipoblastoma ; Labia ; Pediatric ; Benign ; Soft tissue tumors ; Adipose tumor
• 刊名：Journal of Pediatric and Adolescent Gynecology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：29
• 期：6
• 页码：e97-e99
• 全文大小：659 K

文摘

Vulvar masses are rare in prepubertal girls. Lipoblastomas are benign adipose tumors that arise from embryonic white fat and occur almost exclusively in infants and children.

Case

An 18-month-old female infant presented with a 2-cm mobile mass in the left labia majora. Imaging and examination revealed normal prepubertal gynecologic structures and a 4.5 cm fatty mass in the left labia. Surgical excision revealed a 3.8 cm well circumscribed adipose tissue mass consistent with maturing lipoblastoma on microscopic examination. Cytogenetic analysis revealed 79,XXX [7]/46,XX[13], a near-triploid clone.

Summary and Conclusion

The differential diagnosis of vulvar masses in children should include lipoblastoma. Although preoperative imaging has limited ability to differentiate lipomatous tumors, magnetic resonance imaging is the modality of choice for evaluating tumor extension and for surgical planning. Treatment is complete surgical excision with close follow-up for at least 5 years because of the high recurrence rate.