Fragile X Mental Retardation Protein Regulates Synaptic and Behavioral Plasticity to Repeated Cocaine Administration
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- 作者：Laura N. Smith1 ; 2 ; Jakub P. Jedynak1 ; 5 ; Miles R. Fontenot3 ; Carly F. Hale2 ; Karen C. Dietz2 ; Makoto Taniguchi1 ; 2 ; Feba S. Thomas2 ; Benjamin C. Zirlin1 ; 2 ; Shari G. Birnbaum2 ; Kimberly M. Huber4 ; Mark J. Thomas5 ; 6 ; Christopher W. Cowan1 ; 2 ; cwcowan@mclean.harvard.edu" class="auth_mail
- 刊名：Neuron
- 出版年：7 May 2014
- 年：2014
- 卷：82
- 期：3
- 页码：645-658
- 全文大小：2728 K
文摘
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FMRP required for cocaine-induced behavioral plasticity and reward
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Key role for FMRP in NAc structural and functional synapse plasticity
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Structural and functional synapse increases not required for behavioral sensitization
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Distinct roles for FMRP in behavioral sensitization and cocaine reward