Role of extracellular vesicles in autoimmune diseases
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- 作者：Delphine Turpina ; 1 ; delphine.turpin@chu-bordeaux.fr" class="auth_mail" title="E-mail the corresponding author ; Marie-Elise Truchetetb ; c ; 1 ; marie-elise.truchetet@chu-bordeaux.fr" class="auth_mail" title="E-mail the corresponding author ; Benjamin Faustinc ; bfaustin@cirid.org" class="auth_mail" title="E-mail the corresponding author ; Jean-Franç ; ois Augustoc ; jfaugust@cirid.org" class="auth_mail" title="E-mail the corresponding author ; Cé ; cile Contin-Bordesa ; c ; cecile.bordes@chu-bordeaux.fr" class="auth_mail" title="E-mail the corresponding author ; Alain Brissond ; a.brisson@cbmn.u-bordeaux.fr" class="auth_mail" title="E-mail the corresponding author ; Patrick Blancoa ; c ; patrick.blanco@chu-bordeaux.fr" class="auth_mail" title="E-mail the corresponding author ; Pierre Duffauc ; e ; pierre.duffau@chu-bordeaux.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Autoimmune diseases ; Systemic lupus erythematosus ; Rheumatoid arthritis ; Extracellular vesicles ; Microparticles ; Exosomes
- 刊名：Autoimmunity Reviews
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：15
- 期：2
- 页码：174-183
- 全文大小：877 K
文摘
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Extracellular vesicles are mainly represented by exosomes and microparticles.
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Because of their heterogeneity the analysis of extracellular vesicles is complex.
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Extracellular vesicles are a source of self-antigens.
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Extracellular vesicles can contain damage as well as pathogen associated molecular patterns.
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Extracellular vesicles are involved in the pathogenesis of autoimmune diseases.