Extracellular vesicles are mainly represented by exosomes and microparticles.
Because of their heterogeneity the analysis of extracellular vesicles is complex.
Extracellular vesicles are a source of self-antigens.
Extracellular vesicles can contain damage as well as pathogen associated molecular patterns.
Extracellular vesicles are involved in the pathogenesis of autoimmune diseases.