Brain State Dependence of Hippocampal Subthreshold Activity in Awake Mice

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• 作者：Brad K. Hulse¹ ; Evgueniy V. Lubenov¹ ; Athanassios G. Siapas¹ ; ² ; ³ ; ⁴ ; ^{thanos@caltech.edu}
• 关键词：brain state ; hippocampus ; ripples ; sharp waves ; large irregular activity ; small irregular activity ; theta ; neuromodulation ; arousal ; membrane potential
• 刊名：Cell Reports
• 出版年：2017
• 出版时间：3 January 2017
• 年：2017
• 卷：18
• 期：1
• 页码：136-147
• 全文大小：22384 K
• 卷排序：18

文摘

Combined intracellular and extracellular recordings of awake hippocampal activity Hippocampal membrane potential statistics are brain state dependent Rapid fluctuations in arousal are mirrored in hippocampal subthreshold activity Ramps in the membrane potential of hippocampal neurons precede ripple onset