- 作者：Malek Bentayeb ; C¨¦cile Billionnet ; Nour Baiz ; Micka?l Derbez ; S¨¦verine Kirchner ; Isabella Annesi-Maesano
- 关键词：Indoor air pollution ; Aged ; Respiratory disease ; COPD ; VOCs ; Aldehydes ; Glycol ethers
- 刊名：Respiratory Medicine
- 出版年：2013
- 出版时间：October, 2013
- 年：2013
- 卷：107
- 期：10
- 页码：1598-1607
- 全文大小：601 K
Summary
The purpose of this study was to explore respiratory health effects of indoor exposures to aldehydes and volatile organic compounds (VOCs) in elderly living in a population-based representative sample of French dwellings and to compare them to the rest of the occupants of the dwellings.Twenty VOCs were objectively measured in 490 main dwellings. The respiratory conditions were assessed through a standardized questionnaire in 1012 inhabitants aged over 15 years, 144 of whom were aged over 65 years. Generalized estimating equations (GEE) were used to model the relationship between respiratory health outcomes and air pollutants concentrations using the median value of the distribution to define elevated exposure.
Similar levels of indoor air pollutants were found in elderly and others. However, associations between breathlessness and living in dwellings with elevated concentrations of toluene and o-xylene respectively were statistically significant in elderly but not in the rest of the population (adjusted odds ratios (AOR(95 % confidence interval)?=?3.36(1.13, 9.98) and 2.85(1.06, 7.68) in elderly vs. 0.91(0.59, 1.39) and 0.79( 0.47, 1.34) in the others respectively). A more pronounced effect of n-decane on past year breathlessness was observed in case of poor ventilation in the dwellings.
Our results showed a higher risk of breathlessness in elderly exposed to indoor air pollution than in the rest of the exposed population. Further investigations are needed to confirm whether this is related to frailty in elderly.