FeSO₄-promoted direct arylation of benzoquinones with ArB(OH)₂ or ArBF₃K

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• 作者：Kimihiro Komeyama ; ^{kkome@hiroshima-u.ac.jp} ; Tetsuya Kashihara ; Ken Takaki
• 关键词：Iron salt ; Direct arylation ; Benzoquinones ; Aryl boronic acids ; Electron transfer reaction
• 刊名：Tetrahedron Letters
• 出版年：2013
• 出版时间：27 February, 2013
• 年：2013
• 卷：54
• 期：9
• 页码：1084-1086
• 全文大小：689 K

文摘

FeSO₄¡¤7H₂O was proven to work as effective promoter for the direct arylation of benzoquinones with aryl boronic acids in the presence of K₂S₂O₈. In the arylation, slow addition of iron solution was crucial to efficiently proceed with the reaction. Interestingly, the Fe-mediated arylation could be converted into a catalytic reaction by using hydroquinones, instead of benzoquinones, or addition of ascorbic acid.