Rv1497 of M. tuberculosis H37Rv was predicted to be involved in lipid metabolism.
Rv1497 demonstrated both esterase and β-lactamase activities.
Serine within ‘SXXK’ motif was identified as catalytic residue in enzymatic activities.
The catalytic residues of Rv1497 were determined to be Ser88, Tyr-175 and His355.
The expression of Rv1497 gene was significantly up-regulated during acidic stress.