Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases
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- 作者：Lionel Tré ; saugues1 ; 6 ; Camilla Silvander1 ; 4 ; 6 ; camilla.silvander@sprintbioscience.com" class="auth_mail ; Susanne Flodin1 ; Martin Welin1 ; Tomas Nyman1 ; Susanne Grä ; slund1 ; Martin Hammarströ ; m1 ; 5 ; Helena Berglund1 ; Pä ; r Nordlund1 ; 2 ; 3 ; par.nordlund@ki.se" class="auth_mail
- 刊名：Structure
- 出版年：6 May 2014
- 年：2014
- 卷：22
- 期：5
- 页码：744-755
- 全文大小：2949 K
文摘
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Structures of INPP5B/phosphoinositide complexes reveal substrate determinants
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Confirmation of the shared catalytic mechanism with AP endonucleases
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Determination of the membrane interacting regions
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Major differences with the previous model based upon SPsynaptojanin