CD103+ Dendritic Cells Control Th17 Cell Function in the Lung
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- 作者：Teresa Zelante1 ; 2 ; teresa.zelante@unipg.it" class="auth_mail" title="E-mail the corresponding author ; Alicia Yoke Wei Wong1 ; 3 ; Tang Jing Ping1 ; Jinmiao Chen1 ; Hermi R. Sumatoh1 ; Elena Viganò ; 1 ; Yu Hong Bing1 ; Bernett Lee1 ; Francesca Zolezzi1 ; Jan Fric1 ; 4 ; Evan W. Newell1 ; Alessandra Mortellaro1 ; Michael Poidinger1 ; Paolo Puccetti2 ; Paola Ricciardi-Castagnoli1 ; paola.castagnoli@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2015
- 出版时间：22 September 2015
- 年：2015
- 卷：12
- 期：11
- 页码：1789-1801
- 全文大小：4547 K
文摘
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Aspergillus-germinated morphotypes induce IL-2 in lung CD103+ dendritic cells
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IL-2 production is dependent on the Ca2+-calcineurin-NFAT pathway
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Deletion of dendritic-cell-derived IL-2 leads to higher mortality upon infection
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Dendritic-cell-derived IL-2 regulates Th17 cell phenotype