Strain-specific impact of the high-pathogenicity island on virulence in extra-intestinal pathogenic Escherichia coli

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• 作者：Mounira Smati^a ; ^b ; ^c ; ¹ ; Giuseppe Magistro^d ; ¹ ; Sandrine Adiba^e ; Andreas Wieser^f ; Bertrand Picard^a ; ^b ; ^c ; Sö ; ren Schubert^f ; ² ; Erick Denamur^a ; ^g ; ^h ; ² ; ^{erick.denamur@inserm.fr}
• 关键词：Escherichia coli ; High pathogenicity island ; Experimental virulence ; Genetic background
• 刊名：International Journal of Medical Microbiology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：307
• 期：1
• 页码：44-56
• 全文大小：1458 K
• 卷排序：307

文摘

The effect of the HPI depends of the genetic background of the E. coli strain. The genes of different functions within the HPI differentially affect the virulence phenotype. The mouse and amoeba experimental virulence models gave similar results.