PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2
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文摘

PRICKLE1 interacts with RICTOR, a member of the mTORC2 protein complex

The PRICKLE1 complex controls actin cytoskeleton organization

The PRICKLE1 complex contributes to cancer cell dissemination

Upregulation of PRICKLE1 in basal breast cancers is correlated to poor prognosis

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