Full spectrum and selected spectrum based multivariate calibration methods for simultaneous determination of betamethasone dipropionate, clotrimazole and benzyl alcohol: Development, validation and application on commercial dosage form
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- 作者：Hany W. Darwisha ; b ; hdarwish75@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; hdarwish@ksu.edu.sa" class="auth_mail" title="E-mail the corresponding author ; Eman S. Elzanfalyb ; eman.elzanfaly@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Ahmed S. Saadb ; ahmedss_pharm@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Abdelaziz El-Bayoumi Abdelaleemb ; ommoaz82@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Betamethasone dipropionate ; Clotrimazole ; Benzyl alcohol ; PCR ; PLS ; ANN ; GA
- 刊名：Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
- 出版年：2016
- 出版时间：5 December 2016
- 年：2016
- 卷：169
- 期：Complete
- 页码：50-57
- 全文大小：496 K
文摘
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No chemometric method has been reported for the mixture determination.
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Applying PLS, PCR and ANN to resolve severely overlapped spectral data
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Application of GA prior to PLS and ANN chemometric models
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Evaluation of the effect of GA as a powerful variable selection tool
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Statistical comparison to investigate the effect of GA on each model