miR-214 decreases the mRNA expression of HTT co-expressed genes which are predicted to be targeted by it.
miR-214 down regulates the expression of MFN2.
Expression of MFN2 is down regulated in STHdhQ111/111 cells compared to STHdhQ7/7 cells.
miR-214 alters the mitochondrial morphology in STHdhQ7/7 cells via MFN2.
miR-214 alters the cell cycle distribution of the STHdhQ7/7 cells via MFN2.