Maternal phthalate exposure during the first trimester and serum thyroid hormones in pregnant women and their newborns
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- 作者：Hui-yuan Yaoa ; 1 ; Yan Hana ; 1 ; Hui Gaoa ; Kun Huanga ; Xing Gea ; Yuan-yuan Xua ; Ye-qing Xub ; Zhong-xiu Jinc ; Jie Shengc ; Shuang-qin Yanb ; Peng Zhua ; Jia-hu Haoa ; jia7218@126.com" class="auth_mail" title="E-mail the corresponding author ; Fang-biao Taoa ; c ; fbtao@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Endocrine disruption ; Phthalate ; Urinary metabolites ; Thyroid hormone ; Pregnancy women ; Newborn
- 刊名：Chemosphere
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：157
- 期：Complete
- 页码：42-48
- 全文大小：297 K
文摘
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We assessed seven phthalate metabolites level of urine samples in pregnancy women.
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We measured thyroid hormone (TH) concentrations in maternal and cord serum.
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The study had a prospective design and large sample size.
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It is the largest study examing THs change on phthalates exposure in pregnancy.
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Phthalates exposure during the first trimester may disrupt maternal THs levels.