Dynamics and role of antibodies to Plasmodium falciparum merozoite antigens in children living in two settings with differing malaria transmission intensity
详细信息 查看全文
- 作者：David Tiga Kangoyea ; c ; DKangoye@kemri-wellcome.org" class="auth_mail" title="E-mail the corresponding author ; d.kangoye.cnrfp@fasonet.bf" class="auth_mail" title="E-mail the corresponding author ; Victorine Atanase Mensahb ; Linda Muthoni Murungic ; Irene Nkumamac ; Issa Nebiea ; Kevin Marshc ; d ; Badara Cisseb ; Philip Bejonc ; d ; 1 ; Faith Hope Among&rsquo ; in Osierc ; 1 ; Sodiomon Bienvenu Sirimaa ; 1
- 关键词：Malaria ; Infants ; Merozoite antigens ; Antibody dynamics ; Protective threshold
- 刊名：Vaccine
- 出版年：2016
- 出版时间：2 January 2016
- 年：2016
- 卷：34
- 期：1
- 页码：160-166
- 全文大小：1440 K
文摘
- •
Antibody dynamics and role in young the infants’ low susceptibility to febrile malaria were investigated.
- •
No evidence for association of antibody titres with clinical protection was found.
- •
Evidence for consistently low antibody titres in high and low transmission areas.
- •
Other antibodies, other antibody-mediated mechanisms or other protecting factors may be operating.