Effects and efficiency of the most common skeletal apatite pre-treatment chemicals were tested.
All the chemicals tested determine some isotopic shift that seems not to be only related to the removal of organic matter.
H2O2 partly dissolves the carbonate fraction of bioapatite, while being not effective at removing organic substance.
NaClO is efficient at removing organics but induces the adsorption of atmospheric CO2 and the precipitation of carbonate.
N2H4·H2O (hydrazine) is efficient at removing organic matter and causes the smallest C and O isotopic shifts.