A new approach for the immobilization of poly(acrylic) acid as a chemically reactive cross-linker on the surface of poly(lactic) acid-based biomaterials

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• 作者：Ksenia S. Stankevich^a ; ^b ; Nadezhda V. Danilenko^a ; ^b ; Ruslan M. Gadirov^c ; Semen I. Goreninskii^a ; Sergei I. Tverdokhlebov^b ; ^tverd@tpu.ru ; Victor D. Filimonov^a
• 关键词：Poly(lactic) acid ; Poly(acrylic) acid ; Surface modification ; Entrapment ; Composite materials ; Fluorescent compounds ; Bovine serum albumin
• 刊名：Materials Science and Engineering: C
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：71
• 期：Complete
• 页码：862-869
• 全文大小：1167 K
• 卷排序：71

文摘

Method of poly(acrylic) acid immobilization on poly(lactic acid) surface was developed. New composite materials made of poly(lactic) and poly(acrylic) acid were produced. The capacity of the poly(acrylic) acid layer varied from 1.5 nmol/cm2 to 0.1 μmol/cm2. Produced composites were modified with protein (BSA) with high binding density.