A composite chitosan-gelatin bi-layered, biomimetic macroporous scaffold for blood vessel tissue engineering

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• 作者：Ravindra V. Badhe^a ; Divya Bijukumar^a ; Dharmesh R. Chejara^a ; Mostafa Mabrouk^a ; ^b ; Yahya E. Choonara^a ; Pradeep Kumar^a ; Lisa C. du Toit^a ; Pierre P.D. Kondiah^a ; Viness Pillay^a ; ^{viness.pillay@wits.ac.za}
• 关键词：Bi-layered tubular scaffold ; Blood vessel tissue engineering ; Chitosan-gelatin composite hydrogel
• 刊名：Carbohydrate Polymers
• 出版年：2017
• 出版时间：10 February 2017
• 年：2017
• 卷：157
• 期：Complete
• 页码：1215-1225
• 全文大小：2141 K
• 卷排序：157

文摘

New glycerol plasticized chitosan-gelatine based elastic and flexible scaffold. New method for the development of macroporous, layered, tubular scaffold. Eudragit ® microsphere size based scaffold porosity control. Biocompatible gelatine degrades faster providing immediate space for cell growth. Chitosan offers mechanical strength and degrade slowly allowing cells to replace it.